Dr Samuel JK Abraham: Brief Profile
Location: Yamanashi-ken, Japan
Profession: Clinician Scientist
Discipline: Medicine
Specialization: Cardiac Surgery; Regenerative Medicine
• Completed primary medical degree in Tirunelveli Medical College Affiliated to Madurai Kamaraj University, India, in 1992. After a year in Pediatric surgery training, joined Yamanashi Medical University, Japan in April 1994. Finished post-graduate training in Cardiac surgery in 1999 and got PhD. Since then, with the Division of Pediatric Cardiac Surgery, Yamanashi University-Faculty of Medicine, Japan till date.
• Lecturer, Centre for advancing clinical research, Yamanashi University; 2012~ till date
• Started research in stem cells under the Nichi-In consortium, Tokyo, Japan in 2000
• Head, R&D, Co-Founder & Director, GN Corporation Co Ltd., Kofu, Japan.(http://www.gncorporation.com)-2002 Till Date
• Founder & Director, Nichi-In Centre for Regenerative Medicine (NCRM), India; 2005~ till date
• Distinguished Visiting Professor Award by the University of Toronto, CIHR TPRM 2012 & 2018.
• Adjunct Faculty, INDICASAT, Panama, April 2012
• Visiting Professor, Tamilnadu Dr MGR Medical University, India (2010-2015)
• Member, Scientific Board, International Stem Cell Academy (http://www.stemcell-academy.com/scientific-board/)
• Chief Strategy Officer (CSO), (Sophy Inc, Japan)
Publications in Regenerative Medicine Immunology & Nutritional sciences: Click here
Publications in Cardiothoracic and Vascular Surgery. Click here
Interests :
1. Translation of bench-side technologies for in vitro cell culture and tissue engineering using nanomaterials and polymers to the bed-side
2. Studying the complexity of physico-chemical-biological interactions by way of reproducing in vitro biomimicking systems with nanomaterials and environments
3. Immortalization and arrest of the process of aging of cells by subjecting them to various physico-chemical-biological environments and influences including zero-gravity of the outer space
4. Development and evolution of immune system through the ladder of phylogeny
5. Poly-extremo tolerance and adaptability across the ladder of phylogeny
6. Gut microbiome, immune systems, pre-biotics and metabolic syndrome
7. Gut-brain axis, pre-biotics and their linking of neurodevelopmental and neurodegenerative diseases
Projects pursued:
- Corneal limbal stem cells, endothelial progenitors, (cesbank.org)
- Hybrid Artificial Corneal Prosthesis (hybridcornea.org)
- Hepatic progenitors for drug toxicology screening,
- Natural killer cell based immunotherapy for cancer & viral infections, (www.aietforcancer.org)
- Human monoclonal antibodies for cancer,
- Cell based therapies for anti-aging,
- In vitro expansion of human hematopoietic stem cells,
- Tissue engineering of human chondrocytes,
- Nanomaterial based scaffolds for cell culture and tissue engineering,
- Dental stem cells.
- Pre-biotics based control of microinflammation and their role in neurological illnesses
- Gut-brain axis, misfolding of alpha-synuclien and neurodegenerative diseases
- Anti-inflammatory and anti-fibrotic potentials of fungal polysaccharides
Patents (applied/granted):
- A method for cultivating cells derived from corneal limbal tissue.
- Corneal endothelial precursor cell transplantation methodology employing a Nanocomposite gel sheet.
- A novel method of cryopreservation of various types of cells
- Influenza neutralizing antibody and method for screening the same
- Buccal epithelium Expanded and Encapsulated in Scaffold-Hybrid Approach to Urethral Stricture (BEES-HAUS)
- Enhancement of cells and increased NO production in microgravity
- Immune system enhancement and modulation in tackling viral infections and carcinogenesis
- Molecules of significance in curtailing organ fibrosis
- Method of beneficial reconstitution of Gut microbiome in tackling neurological illnesses
- Method to activate endogenous melatonin in children with Autism Spectrum Disorder
Blogs :
Nature Biotech Blog | Nature Bioengineering Community
Other Websites :
http://www.chennaicellcluster.org